Calcium- and sodium-activated potassium channels (K<sub>Ca</sub>, K<sub>Na</sub>) in GtoPdb v.2023.1
نویسندگان
چکیده
Calcium- and sodium- activated potassium channels are members of the 6TM family K which comprises voltage-gated KV subfamilies, including KCNQ subfamily, EAG subfamily (which includes hERG channels), Ca2+-activated Slo (actually with 6 or 7TM) Ca2+- Na+-activated SK (nomenclature as agreed by NC-IUPHAR Subcommittee on sodium-activated [126]). As for 2TM family, pore-forming a subunits form tetramers heteromeric may be formed within subfamilies (e.g. KV1.1 KV1.2; KCNQ2 KCNQ3).
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ژورنال
عنوان ژورنال: IUPHAR/BPS guide to pharmacology CITE
سال: 2023
ISSN: ['2633-1020']
DOI: https://doi.org/10.2218/gtopdb/f69/2023.1